No you cannot. Response.End() ends all responses for the page. So any code placed after that will not have any effect on the page.
Instead , remove the Response.End() and use only Response.Redirect(). It will achieve the result you want.
On other thoughts, you can programatically set the selectedIndex property of the dropdowns to default or clear the textboxes like this
TextBox1.Text = String.Empty;
DropDownList1.SelectedIndex = -1;