yes i got it, Connection To Database: Using Web>config(VB)
just im adding answer as it might help someone
in web.config
<connectionStrings>
<add name="MainConnStr" connectionString="Provider=Microsoft.Jet.OLEDB.4.0;Data Source=E:\vana\Anil\kan.mdb;"/>
</connectionStrings>
and in .aspx.vb
strconnection = New OleDbConnection(ConfigurationManager.ConnectionStrings("MainConnStr").ConnectionString)
strconnection.Open()