I got solution by myself and solution is below..
You can remove the link and call the function before saving document...
PDFDoc doc = new PDFDoc(fileIn);
RemoveCertainExistingLinks(doc, ExcusableLinks);
doc.Save(fileOut, pdftron.SDF.SDFDoc.SaveOptions.e_linearized);
public void RemoveCertainExistingLinks(PDFDoc doc, ICollection<string> excusedLinks)
{
for (PageIterator itr = doc.GetPageIterator(); itr.HasNext(); itr.Next())
{
Page p = itr.Current();
int numAnnots = p.GetNumAnnots();
int i = numAnnots;
while (i != 0)
{
i--;
Annot annot = p.GetAnnot(i);
if (annot.GetType() != Annot.Type.e_Link || !annot.IsValid())
{
continue;
}
pdftron.PDF.Action linkAction = annot.GetLinkAction();
if (linkAction.GetType() != pdftron.PDF.Action.Type.e_URI)
{
continue;
}
pdftron.SDF.Obj sdfobj = linkAction.GetSDFObj();
pdftron.SDF.Obj URIobj = sdfobj.FindObj("URI");
string URI = URIobj.GetAsPDFText();
p.AnnotRemove(i);
}
}
}