add like this you can set any thing by using Item style
<asp:gridview id="grdUsers" runat="server" xmlns:asp="#unknown">
AutoGenerateColumns="False" >
<columns>
<asp:boundfield datafield="name" headertext="Name" />
<asp:boundfield datafield="Gujarati" headertext="Gujarati" >
<ItemStyle ForeColor="#0099FF" />
</asp:BoundField>
</columns>