Dim templateCol As New DataGridTemplateColumn()
templateCol.CellTemplate = XamlReader.Load("<DataTemplate xmlns='http://schemas.microsoft.com/client/2007'" & vbCr & vbLf & vbCr & vbLf & "xmlns:x='http://schemas.microsoft.com/winfx/2006/xaml'><ComboBox x:Name='comb' /> </DataTemplate>")
Datagrid.Columns.Add(templateCol)