Please see my comment to the question. As ASP.NET works with HTTP (HTTPS), not with e-mail protocols, the question makes no sense. There is nothing to "configure". It would make sense if you simply explained what do you want to do with e-mail (no, "receive" is not an unambiguous definition of it) and what functionality you want. It is possible that you don't need anything related to ASP.NET but need to setup, say, SMTP-based service. Or do you need a Web front-end to a post boxes with stored messages? They you would need to work with SMTP or IMAP.
Please see:
http://en.wikipedia.org/wiki/E-mail[
^],
http://en.wikipedia.org/wiki/SMTP[
^],
http://en.wikipedia.org/wiki/Mail_server[
^], see also "Transfer versus Access" section,
http://en.wikipedia.org/wiki/Post_Office_Protocol[
^],
http://en.wikipedia.org/wiki/Internet_Message_Access_Protocol[
^].
If you determine for yourself what exactly do you need, you will probably find a lot of help. For example, see on CodeProject:
http://www.codeproject.com/search.aspx?q=POP3+%22C%23%22[
^],
http://www.codeproject.com/search.aspx?q=Pop3+%22C%23%22[
^].
—SA